INTERNEURON HETEROTOPIA IN THE LIS1 MUTANT MOUSE CORTEX UNDERLIES A STRUCTURAL AND FUNCTIONAL SCHIZOPHRENIA-LIKE PHENOTYPE

Interneuron Heterotopia in the Lis1 Mutant Mouse Cortex Underlies a Structural and Functional Schizophrenia-Like Phenotype

LIS1 is one of the Collections principal genes related to Type I lissencephaly, a severe human brain malformation characterized by an abnormal neuronal migration in the cortex during embryonic development.This is clinically associated with epilepsy and cerebral palsy in severe cases, as well as a predisposition to developing mental disorders, in ca

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Characterization of a new full length TMPRSS3 isoform and identification of mutant alleles responsible for nonsyndromic recessive deafness in Newfoundland and Pakistan

Abstract Background Mutant alleles of TMPRSS3 are associated with nonsyndromic recessive deafness (DFNB8/B10).TMPRSS3 encodes a predicted secreted serine protease, although the deduced amino acid sequence has no signal peptide.In this study, we searched for mutant alleles of TMPRSS3 in families from Pakistan and Newfoundland with recessive deafness

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The economical freedom in the Islamic thinking

The economical Freedom is consider one of the issues that took great deal of attention in the Islamic economy for its importance in achieving the economical development by granting the acquiring freedom for the individuals in gaining and getting the fruits of their efforts S.R. CALME MENTAL of work and studying where the goal of this freedom is put

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